EQUELLE, the equol-containing supplement, could be the answer to maintain your health and beauty. (Find out where to buy in Osaka area!)

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Written by Editorial department

Have you noticed any mental or physical changes since reaching your forties? As many of you might know, Oronine H Ointment, that we just introduced in the previous article, has been a staple in many Japanese households for over 60 years. What you might not know is that it's manufactured by Japan's Otsuka Pharmaceutical Group.

*This is a republished article which was originally published on November 24, 2016.

Otsuka Pharmaceutical Group manufactures a wide range of products, including various pharmaceuticals, functional foods and beverages, and more.

Examples of some of Otsuka Pharmaceutical Group’s many products
Examples of some of Otsuka Pharmaceutical Group’s many products

Today we'd like to talk about the exciting new supplement EQUELLE. It contains equol, an ingredient that helps women over 40 with decreasing female hormone levels staying healthy and beautiful during their time of transition.


Product Name
73.9g (660mg x 112 tablets) for 28 days’ supply

The hormone estrogen plays many important roles in the bodies of women. It governs menstruation and pregnancy, as well as affects the condition of your skin, hair, blood vessels, bones, etc. However, from around the age of 40, the estrogen level begins to drop, causing a number of discomforts.

Perhaps you’ve heard about soy isoflavones (a component of soybeans) before; they function very similarly to estrogen, which is why they were considered to ease the discomforts associated with menopause. However, recent research has shown that only a limited number of populations produces Equol by metabolizing the soy isoflavone daidzein with their intestinal bacteria, benefiting even more as Equol functions more similar to that of estrogen! The focal point is whether you are Equol producer or not.

Some research has found that only approximately 50% of Japanese and 20-30% of North Americans were able to produce equol. That’s where Otsuka Pharmaceutical stepped in. Through their research, they were able to identify lactic acid bacteria as the key to the production of equol, and with this new finding they developed EQUELLE! This EQUELLE is a natural supplement made naturally from only food products (soybeans fermented in lactic acid bacteria) without combining, extracting, or concentrating. It is safe and can be taken daily.

Have you noticed any mental or physical changes since reaching your forties? For example, hot flashes, a pounding heartbeat, constant feelings of irritation, anxiety, and depression, etc. EQUELLE may be just what you need to start feeling like yourself again!

While this product can be found at most drug stores with pharmacies in Japan, we’ve taken the liberty of listing 3 in the Osaka area that we know it can be purchased from.

Address:3-5-17, Minamisenba, Chuo-ku, Osaka-shi, Osaka
Business Hours:9:30-20:00/Sun, National Holiday 11:00-19:00

【Futatsuka pharmacy NAMBA PARKS】
Address:2-10-70 Nambanaka, Naniwa-ku, Osaka-shi, Osaka
Business Hours:Monday-Friday 9:00-20:00/Saturday 9:00-14:00 ※Closed: Sundays & Holidays

【Niziiro Drugstore Shinsaibashi】
Address:2F, 2-2-22, Shinsaibashi-suji, Chuo-ku, Osaka-shi, Osaka
Business Hours:Monday-Friday 11:00-20:00/Saturday & Sunday 11:00-17:00 ※Closed: Second Wednesday & Holidays